Latest Publications

 

Astrocytes in nTS after vagotomy
Hofmann et al. Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat
AJP Reg. 2021
PubMed PMID: 33978480
GATs control IPSCs
Martinez, Lima-Silveira, Matott et al.   Gamma-Aminobutyric Acid Transporters in the Nucleus Tractus Solitarii Regulate Inhibitory and Excitatory Synaptic Currents That Influence Cardiorespiratory Function
Frontiers Physiol
PubMed PMID: 35095576

2022

Martinez D, Lima-Silveira L, Matott MP, Hasser EM, Kline DD. Gamma-Aminobutyric Acid Transporters in the Nucleus Tractus Solitarii Regulate Inhibitory and Excitatory Synaptic Currents That Influence Cardiorespiratory Function. Front Physiol. 2022 Jan 14;12:821110. doi: 10.3389/fphys.2021.821110. PMID: 35095576; PMCID: PMC8795970.

2021

Hofmann GC, Hasser EM, Kline DD. Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat. Am J Physiol Regul Integr Comp Physiol. 2021 Jun 1;320(6):R945-R959. doi: 10.1152/ajpregu.00019.2021. Epub 2021 May 12. PMID: 33978480; PMCID: PMC8285617.

Martinez D, Kline DD. The role of astrocytes in the nucleus Tractus Solitarii in maintaining central control of autonomic function. Am J Physiol Regul Integr Comp Physiol. 2021 Jan 13. doi: 10.1152/ajpregu.00254.2020. Epub ahead of print. PMID: 33439770.

2020

Domingos-Souza G, Martinez D, Sinkler S, Heesch CM, Kline DD (2020) Alpha adrenergic receptor signaling in the hypothalamic paraventricular nucleus is diminished by the chronic intermittent hypoxia model of sleep apnea. Exp Neurol. 2020 Oct 23;335:113517. doi: 10.1016/j.expneurol.2020.113517. Epub ahead of print. PMID: 33132201.

Lima-Silveira L, Martinez D, Hasser EM, Kline DD. Mechanisms Underlying Neuroplasticity in the Nucleus Tractus Solitarii Following Hindlimb Unloading in Rats. Neuroscience. 2020 Oct 9:S0306-4522(20)30623-0. doi: 10.1016/j.neuroscience.2020.09.043. Epub ahead of print. PMID: 33039526.

Dantzler HA, Kline DD. Exaggerated potassium current reduction by oxytocin in visceral sensory neurons following chronic intermittent hypoxia. Auton Neurosci. 2020 Sep 28;229:102735. doi: 10.1016/j.autneu.2020.102735. Epub ahead of print. PMID: 33032244.

Martinez D, Rogers RC, Hasser EM, Hermann GE, Kline DD. Loss of excitatory amino acid transporter restraint following chronic intermittent hypoxia contributes to synaptic alterations in nucleus tractus solitarii. J Neurophysiol. 2020 Jun 1;123(6):2122-2135. doi: 10.1152/jn.00766.2019. Epub 2020 Apr 29. PMID: 32347148; PMCID: PMC7311725.

Matott MP, Hasser EM, Kline DD. Sustained Hypoxia Alters nTS Glutamatergic Signaling and Expression and Function of Excitatory Amino Acid Transporters. Neuroscience. 2020 Mar 15;430:131-140. doi: 10.1016/j.neuroscience.2020.01.034. Epub 2020 Feb 4. PMID: 32032667; PMCID: PMC7560968.

Martinez D, Rogers RC, Hermann GE, Hasser EM, Kline DD. Astrocytic glutamate transporters reduce the neuronal and physiological influence of metabotropic glutamate receptors in nucleus tractus solitarii. Am J Physiol Regul Integr Comp Physiol. 2020 Mar 1;318(3):R545-R564. doi: 10.1152/ajpregu.00319.2019. Epub 2020 Jan 22. PMID: 31967862; PMCID: PMC7099463.

2019

Ruyle BC, Martinez D, Heesch CM, Kline DD, Hasser EM. The PVN enhances cardiorespiratory responses to acute hypoxia via input to the nTS. Am J Physiol Regul Integr Comp Physiol. 2019 Dec 1;317(6):R818-R833. PubMed PMID: 31509428; PubMedCentral P MCID: PMC6962628.

Milanick WJ, Polo-Parada L, Dantzler HA, Kline DD. Activation of alpha-1 adrenergic receptors increases cytosolic calcium in neurones of the paraventricular nucleus of the hypothalamus. J Neuroendocrinol. 2019 Oct;31(10):e12791. PubMed PMID: 31494990; PubMed Central PMCID: PMC7003713.

Dantzler HA, Matott MP, Martinez D, Kline DD. Hydrogen peroxide inhibits neurons in the paraventricular nucleus of the hypothalamus via potassium channel activation. Am J Physiol Regul Integr Comp Physiol. 2019 Jul 1;317(1):R121-R133. PubMed PMID: 31042419; PubMed Central PMCID: PMC6692749.

Kline DD, Wang S, Kunze DL. TRPV1 channels contribute to spontaneous glutamate release in nucleus tractus solitarii following chronic intermittent hypoxia. J Neurophysiol. 2019 Mar 1;121(3):881-892. PubMed PMID: 30601692; PubMed Central PMCID: PMC6520621.

Matott MP, Kline DD, Hasser EM. Glial EAAT2 regulation of extracellular nTS glutamate critically controls neuronal activity and cardiorespiratory reflexes. J Physiol. 2017 Sep 1;595(17):6045-6063. PubMed PMID: 28677303; PubMed Central PMCID: PMC5577520.

Full list and text of publications can be found on Pubmed

Book chapters and abstracts can be found on Google Scholar